Exposure Assessment Approaches for Engineered Nanomaterials
نویسندگان
چکیده
منابع مشابه
Exposure assessment approaches for engineered nanomaterials.
Products based on nanotechnology are rapidly emerging in the marketplace, sometimes with little notice to consumers of their nanotechnology pedigree. This wide variety of nanotechnology products will result (in some cases) in unintentional human exposure to purposely engineered nanoscale materials via the dermal, inhalation, ingestion, and ocular pathways. Occupational, consumer, and environmen...
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The use of alternatives assessment to substitute hazardous chemicals with inherently safer options is gaining momentum worldwide as a legislative and corporate strategy to minimize consumer, occupational, and environmental risks. Engineered nanomaterials represent an interesting case for alternatives assessment approaches, because they can be considered both emerging "chemicals" of concern, as ...
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A systematic, tiered approach to assess the safety of engineered nanomaterials (ENMs) in foods is presented. The ENM is first compared to its non-nano form counterpart to determine if ENM-specific assessment is required. Of highest concern from a toxicological perspective are ENMs which have potential for systemic translocation, are insoluble or only partially soluble over time or are particula...
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Engineered nanomaterials (ENMs) are used in a broad spectrum of consumer products. The particle size at the nano-range gives ENMs particular physicochemical properties that may lead to exceptional performance regarding parameters such as e.g. surface reactivity, conductivity, porosity, solubility, crystallinity, optical sensitivity, bio-persistence, etc. Apart from a large range of potential be...
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Some engineered nanomaterials (ENMs) may have the potential to cause damage to the genetic material in living systems. The mechanistic machinery functioning at the cellular/molecular level, in the form of DNA repair processes, has evolved to help circumvent DNA damage caused by exposure to a variety of foreign substances. Recent studies have contributed to our understanding of the various DNA d...
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ژورنال
عنوان ژورنال: Risk Analysis
سال: 2010
ISSN: 0272-4332
DOI: 10.1111/j.1539-6924.2010.01446.x